Although tocopherols and tocotrienols are available from the diet, α-tocopherol is the primary form of vitamin E found and maintained in the body, due to the specificity of a transport protein for α-tocopherol (see the article on Vitamin E). Tocotrienols, which are found in the body to a lesser extent, also exist in four different forms (α-, β-, γ-, and δ-tocotrienol). Tocopherols are the most abundant form of vitamin E in the body, consisting of four different forms (α-, β-, γ-, and δ-tocopherol). The term “vitamin E” does not refer to a single molecule but to two classes of molecules with similar structures and antioxidant properties, comprising a family of eight substances. This article discusses the roles of vitamin E in the skin and summarizes the current knowledge about vitamin E in skin health. Other roles of vitamin E in the skin are poorly understood because research is limited. Vitamin E may also have related anti- inflammatory roles in the skin. Thus, it plays important roles in photoprotection, preventing UV-induced free radical damage to skin. In addition, vitamin E can also absorb the energy from ultraviolet (UV) light. As an antioxidant, vitamin E primarily reacts with reactive oxygen species. Topical application can also supply the skin with vitamin E and may provide specific vitamin E forms that are not available from the diet. Vitamin E is normally provided to the skin through the sebum. Vitamin E is also found as vitamin E conjugates that increase stability but require cellular metabolism for activation. Naturally occurring vitamin E is not a single compound instead, vitamin E is a group of molecules with related structures, some of which may have unique properties in skin. Vitamin E is a fat-soluble antioxidant that is essential for the maintenance of healthy skin. See the Skin Health Overview article Overview Healthcare Professional Continuing Education.Chlorophyll and Metallo-Chlorophyll Derivatives.
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